Vitamin B6 (Pyridoxal-5-Phosphate, P-5-P)

April 19, 2018

This is another ingredient where Akua Life upgraded the potency of the common compound Vitamin B6 to Vitamin B6 (Pyridoxal-5-Phosphate, P-5-P). P-5-P does all that vitamin B6 does and is more bio-available.

The potency will be apparent with the results you will achieve in your mind and body while taking Neuro-Stack! Superior Ingredients Equal Unprecedented Results!

The following is quoted from NootropicExpert.com with written authorized permission from David Tomen the author and creator of the NootropicExpert.com, the authority on nootropics.

Vitamin B6 (Pyridoxine, Pyridoxal, Pyridoxamine) is one of 8 B-vitamins. B6 is water-soluble and found in every single cell in your body.

Vitamin B6 is known to enhance alertness, cognition, energy, elevate mood, lower anxiety and normalize homocysteine levels.

Vitamin B6 a required coenzyme for the synthesis of dopamine, epinephrine, GABA, melatonin, norepinephrine, and serotonin.[i]

As a nootropic, Vitamin B6 is crucial for the synthesis of these neurotransmitters. Even mild deficiency results in down-regulation of GABA and serotonin synthesis. Leading to poor sleep, behavior, cardiovascular function, and the loss of hypothalamus-pituitary control of hormone secretion.[ii]

Vitamin B6 was first isolated in the 1930’s. The “6” in Vitamin B6 refers to six common forms, namely pyridoxal, pyridoxine (pyridoxol), pyridoxamine, and their phosphorylated forms.

Pyridoxal phosphate (pyridoxal 5′-phosphate, P-5-P, PLP), the active form of Vitamin B6 is said to be the most versatile organic cofactor in biology. More than 140 distinct enzyme activities in your body and brain depend on PLP.[iii]

The biochemical reactions in your body by PLP-dependent enzymes include the making of hemoglobin, amino acid synthesis, and fatty acid metabolism.

PLP also functions as a coenzyme that catalyzes the release of glucose from stored glycogen. Turning it into the type of energy your brain cells can use for fuel.

Vitamin B6 (Pyridoxine) helps:

  • Cerebral Circulation: Vitamin B6 is needed to regulate homocysteine. High homocysteine levels are linked to inflammation that can lead to blood vessel damage. And possible plaque buildup leading to heart attack or stroke.
  • Neurotransmitters: Vitamin B6 is a cofactor in the synthesis of neurotransmitters dopamine, epinephrine, GABA, norepinephrine, and serotonin. Affecting alertness, cognition, memory, and mood.

Mood: Vitamin B6 helps increase brain serotonin and dopamine levels. Decreasing anxiety, depression, fatigue, and pain.

 

 



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