DMAE (Dimethylaminoethanol, Deanol, Deaner) AND REASONS NOT TO USE IT, ESPECIALLY IN A DAILY STACK.
It may be true that DMAE improves cognitive functions like many other nootropics, but as we dug a little deeper into DMAE, we found two clinical studies that made us realize 100% there was no way DMAE would ever make it into our masterpiece, Neuro-Stack. We do not believe that DMAE should even be called a nootropic, and after you read the information from the clinical studies, you may feel the same as we do. We concluded that this is one nootropic to steer clear of, let us share our journey to this decision.
During the infancy stages of the development of Neuro-Stack, DMAE was one of the ingredients on the list to be considered. It was at the top of the list because it is well known, seemed to produce results, and it was incredibly inexpensive, which makes it extremely profitable!
DMAE is one of the cheapest nootropics available behind the cheapest ever, Huperzine-A. You can buy DMAE on Amazon (as of May 2018), for under 3 cents per dose, which is 90 cents for a months supply, retail! Even if we bought at retail, the mark up for resale is still over 500%! The profit margins are so vast that there is no way to lose putting DMAE into your stack, and this is most likely the main reason so many stacks have DMAE in them. It benefits any company to add DMAE to their stack because of the ridiculous profit margin but from our research, not so pleasant for the people consuming it.
What we are about to share with you is either unknown, overlooked, or just ignored by our competitors. Let us assume that other companies using DMAE are not informed of the risks of DMAE; this makes it at least ethical. The reasons or excuses for missing this extremely important information are quite frankly unacceptable in our opinion.
Companies of the future must step up and put the consumer and the planet before the profit, and give back with part of the profits. At Akua Life, we strive to do just that. Customer safety and satisfaction is considered more important than profit, we are continually looking for ways to make our product more Eco-friendly, and we give back a portion of our profits to helping Alzheimer's patients. Money is not the driving force at Akua Life.
The eight driving forces of Akua Life are simple
Love, Quality, Potency, Results, Helping People, Health Wellness and Being Eco-Friendly are all precursors and very necessary in our opinion for making our biggest goal easy to obtain, Creating Happy Customers!
Even though DMAE was going to make us a lot of money because of the hefty profit margin, it got scratched off the Neuro-Stack ingredients list PRONTO!
Let's start with three quotes from a well-known medical doctor, Dr. Andrew Weil. After reading these quotes feel free to look into the clinical studies themselves which show developmental abnormality in mice embryos and side effects in human beings which included retardation and increased confusion.
“Evidence that DMAE actually influences acetylcholine levels are contradictory, so I wouldn’t count on supplements to yield positive effects.”
“One study published in 1979 linked DMAE with depression and moderate symptoms of mania (hypomania).”
“I currently see no evidence that taking it will do anyone any good.”
Dr. Andrew Weil
The side effects of daily DMAE usage sneak up on you, you may not even know that DMAE is the culprit because they are common issues. Headaches, depression, confusion, insomnia, tense muscles, tightness in the jaw, neck or shoulders, increased blood pressure, gastrointestinal problems, confusion, drowsiness, body odor, and irritability. Those with bipolar disorder may experience an increase in symptom severity as well as frequency. Also, those with diagnosed epilepsy, or a history of convulsions, should not use DMAE.
DMAE inhibits choline and the metabolism of choline, this is a serious problem especially since you 100% need choline and acetylcholine for your brain to operate to its full potential. [i]
According to the research done by the National Center for Biotechnology Information (NCBI). A disruption in choline intake created by DMAE resulted in developmental abnormalities in the neurulation mouse embryos. If you are pregnant, and you take DMAE, there is a good chance that you may have developmental abnormalities and growth retardation in your embryo.
Since humans share 69.6% of the same genes as mice and are creating new cells daily, it was a big deal to our research and executive teams. [ii]
We saw this as a serious enough problem to not think further about adding it to Neuro-Stack. We did not feel comfortable putting ingredients in our stack that created birth defects and developmental abnormalities in ANY embryos.
Still not convinced to give up DMAE? Here comes the grand slam.
The National Center for Biotechnology Information (NCBI) is part of the United States National Library of Medicine (NLM), a branch of the National Institutes of Health (NIH). The NCBI posted research concerning a double-blind, placebo-controlled trial in 1981 of which 2-dimethylaminoethanol was undertaken in 27 patients with moderately severe or severe Alzheimer's disease. Of the 13 patients in the drug group, six or 46% were withdrawn in the first five weeks of the trial because of side effects! The side effects included retardation, increased confusion, drowsiness, and elevation of blood pressure. "No significant benefit appeared from the drug treatment." That is the nail in the coffin for DMAE; we will never use it in any blend, ever.
All of the ingredients in Neuro-Stack are safe for daily use. Thousands and thousands of hours and meticulous care were taken in the development, research, and selection of the ingredients in Neuro-Stack. Many of the ingredients in Neuro-Stack compliment each other and have a synergetic effect, similar to the synergetic effect of THC & CBD.
CONCLUSION ABOUT DMAE: It makes good financial sense for a company to add DMAE for profit. Because of the effect of DMAE on mice embryos, and the clinical study that people were "withdrawn because of the side effect of retardation and confusion." We concluded that is not worth the risk. With so many choices of nootropics, today why bother with the cheap and dangerous DMAE? 100% if you are planning on being pregnant or are pregnant, do not use DMAE. We did not want our customers to have any possible chance of retardation, confusion, drowsiness, high blood pressure, or developmental abnormalities during pregnancy. Bottom line "Just say no to DMAE."
HUPERZINE-A AND REASONS NOT TO USE IN A DAILY STACK.
Yes, it is true, Huperzine-A improves neurotransmitters, memory, and cognition. The effects of Huperzine-A are fantastic as is true for many of the nootropics available today!
During the infancy stages of the development of Neuro-Stack, Huperzine-A was one of the ingredients on the list to be considered as well. It was at the top of the list because it is well known, it gets results, it is incredibly inexpensive and extremely profitable. Maybe the cheapest nootropic available, ever! You can buy it on Amazon (as of May 2018) for .0006 cents per dose, retail! That is less than 2 pennies for a months supply! From a capitalistic viewpoint, Huperzine-A is the star child to becoming a Gazillionaire!
Maybe that is why what we are about to share with you gets overlooked and not spoken about. Maybe companies do not know or care what we are going to share with you, it is an expensive piece of information, for the company. It is a 600,000% markup in price, minimum!
Financially speaking, it would benefit any company to add it to their stack because of the ridiculous profit margin, excellent for the corporation selling the nootropic. We found research that shows it is not so pleasant for the people consuming it in a daily nootropic stack.
Huperzine-A can be toxic in large amounts. You may not even know that you are suffering from Huperzine-A overdose. It creeps up on you with symptoms of insomnia, anxiety, high blood pressure, slowed heart rate, restlessness, sweating, loss of appetite, contraction of muscle fibers, constipation, and twitching. These are the typical, less severe problems of taking Huperzine-A every day. A few of the more severe complications are dizziness, nausea, cramping, muscle tremors, blurred vision, slurred speech, and even drooling. Obviously, we do not want to consume large amounts of Huperzine-A, and by large amounts, we are talking about a minimal amount. Try not to consume over 200mcg once every two or three days.
Huperzine-A's has a half-life of at least 24 hours. Half-life means 50% of a substance you consume would still be in your body after a certain amount of time, in this case after 24 hours or more.
Let's say you take 200mcg on day one, day two you take 200mcg more, 100mcg is still in your body from day one, now you are at 300mcg that is too much, and your body never gets a chance to repair and build neuro-pathways without it. We do not want that. We believe the purpose of a nootropic stack is to aid the body, not to become a lifetime crutch.
CONCLUSION ABOUT HUPERZINE-A: When taking Huperzine-A, cycling is a must, and it should not be consumed every day because of its long half-life. Remember Huperzine-A's half-life is a minimum of 24 hours. It adds up quickly, and large amounts are toxic.
Buy it separately and cycle it every 2 or 3 days. Do not use Huperzine-A in a daily stack for two reasons: 1. Why pay a 600,000% mark up? 2. It can create havoc on your body if taken every day because of its half-life. Find a different nootropic to use or at very least do not use Huperzine-A every day. Just say no to Huperzine-A in your daily stack.
BOTTOM LINE CONCERNING HUPERZINE-A & DMAE
We chose not to use DMAE AND HUPERZINE-A in our stack, ever, period. With so many choices on the market today, the reward versus the risk is not worth it. If you do decide to use them, then buy them separately. Literally, it costs a manufacturer less than ONE DOLLAR for a months supply of DMAE and Huperzine-A, why pay such an astronomical markup and have possible health risks too?
Be more discerning when it comes to your nootropic stack. Read the labels and get the highest potency possible. Our ingredients label on our bottle is extra large, so you can actually read it without a magnifying glass! We do this for total transparency. Notice how available the ingredient list is everywhere concerning Neuro-Stack. The ingredients are our number one selling point! Please read and compare our ingredients to any stack on the market today and you will see the EXTREME value in Neuro-Stack. Notice the potency percentages and the purity of all our ingredients. You will see we outshine everyone in the world.